Eduard Grebe, PhD

Research Associate

Eduard is a Researcher who works primarily on HIV incidence estimation. He was the principal analyst for the CEPHIA collaboration, an international consortium established to independently evaluate HIV incidence assays (i.e. laboratory tests for ‘recent’ HIV infection, used in cross-sectional incidence estimation) and serves on the World Health Organisation’s technical working group on HIV incidence assays. He is also the maintainer of the open source inctools package for the R statistical programming language, which provides implementations of standard methods for cross-sectional incidence estimation and for ‘calibrating’ tests for recent infection. He has a background in social science, having obtained his PhD in economics from the University of Cape Town for work on HIV/AIDS policy and civil society health activism in Sub-Saharan Africa.

ORCID ID: 0000-0001-7046-7245

Recent publications

Smoothing age/time structure of HIV prevalence, for optimal use in synthetic cohort based incidence estimation
Mhlanga L, Grebe PE, Welte A

medRxiv

(2021)

https://doi.org/10.21203/rs.3.rs-959136/v1
SARS CoV-2 infection fatality rate estimates for South Africa
Mhlanga L, Vermeulen M, Grebe PE, Welte A

medRxiv

(2021)

https://doi.org/10.21203/rs.3.rs-707813/v2
Prevalence of anti-SARS-CoV-2 antibodies among blood donors in Northern Cape, KwaZulu-Natal, Eastern Cape, and Free State provinces of South Africa in January 2021
Sykes W, Mhlanga L, Swanevelder R, Glatt TN, Grebe PE, Coleman C, Pieterson N, Cable R, Welte A, van den Berg K, Vermeulen M

Research Square

(2021)

https://doi.org/10.21203/rs.3.rs-233375/v1
Estimated dates of detectable infection (EDDIs) as an improvement upon Fiebig staging for HIV infection dating
Facente SN, Grebe PE, Pilcher CD, Busch MP, Murphy G, Welte A

Epidemiology and Infection

(2020)

https://doi.org/10.1017/S0950268820000503
Interpreting HIV diagnostic histories into infection time estimates: analytical framework and online tool
Grebe PE, Facente SN, Bingham JL, Pilcher CD, Powrie A, Gerber J, Priede G, Chibawara T, Busch MP, Murphy G, Kassanjee R, Welte A

BMC Infectious Diseases

(2019)

https://doi.org/10.1186/s12879-019-4543-9
Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for HIV incidence surveillance
Sempa JB, Welte A, Busch MP, Hall J, Hampton D, Facente SN, Keating SM, Marson K, Parkin N, Pilcher CD, Murphy G, Grebe PE

PLoS One

(2019)

https://doi.org/10.1371/journal.pone.0220345
Evaluation of the performance of three biomarker assays for recent HIV infection using a well-characterized HIV-1 subtype C incidence cohort
Gonese E, Kilmarx PH, van Schalkwyk C, Grebe PE, Mutasa K, Ntozini R, Parekh BS, Dobbs T, Pottinger YD, Masciotra S, Owen M, Nachega JB, van Zyl G, Hargrove JW

AIDS Research And Human Retroviruses

(2019)

https://doi.org/10.1089/aid.2019.0033
A generalizable method for estimating duration of HIV infections using clinical testing history and HIV test results
Pilcher C, Porco TC, Facente SN, Grebe PE, Delaney KP, Silvina M, Kassanjee R, Busch MP, Murphy G, Owen SM, Welte A

AIDS

(2019)

https://doi.org/10.1097/QAD.0000000000002190
Challenges to the performance of current HIV diagnostic assays and the need for centralized specimen archives: a review of the Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA) repository
Facente SN, Busch MP, Grebe PE, Pilcher CE, Welte A, Rice B, Murphy G

Gates Open Research

(2019)

https://doi.org/10.12688/gatesopenres.13048.1
Assessment of HIV transfusion transmission risk in South Africa: a 10-year analysis following implementation of individual donation nucleic acid amplification technology testing and donor demographics eligibility changes
Vermeulen M, Lelie N, Coleman C, Sykes N, Jacobs G, Swanevelder R, Busch MP, van Zyl G, Grebe PE, Welte A, Reddy R

Transfusion

(2019)

https://doi.org/10.1111/trf.14959