Larisse Bolton, PhD

Researcher

Research theme: Optimising Health Systems

Larisse Bolton holds a BSc in Chemistry and a PhD in Applied Mathematics from the University of the Free State in Bloemfontein, South Africa. Her postgraduate research focused on the application of mathematical modelling in oncology using different approaches – model adaptation and model construction. She was a postdoctoral research fellow at the DSI-NRF Centre of Excellence in Epidemiological Modelling and Analysis (SACEMA) in Stellenbosch from 2018-2021 and now holds the position of Researcher at SACEMA. Her current research focuses on blood systems analysis. She has been assessing blood product usage and demand in South Africa and is developing a predictive model for red blood cell product usage. The model will be used to investigate various scenarios of health system structuring.

ORCID ID: 0000-0001-7879-2173

Recent publications

Epidemiology of healthcare-associated bloodstream infection in South African neonatal units
Dramowski A, Bolton L, Bekker A, Engelbrecht A, Esasmus L, Fataar A, Geldenhuys C, Kunneke M, Le Roux D, O'Connel N, Reddy K, Rhoda N, Tooke L, Wates M, Wessels T, van Schalkwyk C, Whitelaw A

BMC Infectious Diseases

(2024)

https://doi.org/10.1186/s12879-024-10219-0
Neonatal sepsis: Challenges in data access, harmonisation and analysis to inform empirical antibiotic recommendations in South African neonatal units
Bolton L, Bekker A, Govender N, van Schalkwyk C, Whitelaw A, Dramowski A

Southern African Journal of Public Health

(2023)

https://doi.org/10.7196/SAJPH.2023.v6.i2.175
Characterising differences in red blood cell usage patterns between healthcare sectors in South Africa: 2014-2019
Bolton L, van den Berg K, Swanevelder R, Pulliam JRC

Blood Transfusion

(2022)

https://doi.org/10.2450/2021.0209-21
Mind the gap: patterns of red blood cell product usage in South Africa, 2014 – 2019
Bolton L, van den Berg K, Swanevelder R, Pulliam JRC

The South African Medical Journal

(2021)

https://doi.org/10.7196/SAMJ.2021.v111i10.15658
Describing the evolution of myeloid-derived leucocytes in treated B-lineage paediatric acute lymphoblastic leukaemia with a data-driven granulocyte-monocyte-blast model
Bolton L, Acho TM, Stones DK, Hui C

Mathematical Medicine and Biology: A Journal of the IMA

(2020)

https://doi.org/10.1093/imammb/dqaa003

Larisse Bolton, PhD

Researcher

Recent publications

Epidemiology of healthcare-associated bloodstream infection in South African neonatal units

Neonatal sepsis: Challenges in data access, harmonisation and analysis to inform empirical antibiotic recommendations in South African neonatal units

Characterising differences in red blood cell usage patterns between healthcare sectors in South Africa: 2014-2019

Mind the gap: patterns of red blood cell product usage in South Africa, 2014 – 2019

Describing the evolution of myeloid-derived leucocytes in treated B-lineage paediatric acute lymphoblastic leukaemia with a data-driven granulocyte-monocyte-blast model